For Pochettino, Lloris's situation is an example of the many distractions that take managers' and players' attentions away from preparing for matches.
His teammate, Dele Alli, has also been ruled out of the Liverpool game after picking up a hamstring injury while on worldwide duty with England.
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In other team news for Tottenham, Juan Foyth returned to training last week after injuring his thigh, while Moussa Sissoko, out with a hamstring injury, is expected to get back to training next week.
Pochettino said that "of course" Lloris would remain captain, explaining: "He's the first that regrets everything".
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Alli missed England's friendly win against Switzerland on Tuesday with a hamstring strain, and Spurs have confirmed he will play no part in their meeting with Jurgen Klopp's side at lunchtime on Saturday.
This could mean a return for Heung-min Son.. "I think he's fit, I have not read or heard what's going on around him, the most important thing for me is that we trust him". We need to try (to see) he understands he made a mistake. "The last two weeks were fantastic for him". "I'm happy because the circumstances of the summer were so different from another season". He needs to adapt and understand and accept that he needs to play with this little bit of pain. You have to accept responsibility for it. "Because he is clever he'll learn and now he is going to move on". "It will be a massive impact for us for the future, and we are so happy that he is so close to being at his best". Drink driving is completely unacceptable.
Liverpool legend says Klopp doesn't need to win silverware this season
Sadly they didn't win a title but now we try to make a step forward and try to win titles. "That for me is more important". If Manchester United can do that on Saturday , I can see them winning the game.
'Of course he doesn't feel great. He said he was guilty and responsible. Then we're all men and women and we can all make mistakes.