The trio looked to be ready to leave Spurs since January, with Dembele and Alderweireld not getting any closer to signing new contracts with Mauricio Pochettino's side.
Toby Alderweireld had an awesome World Cup where he played a key role in helping Belgium finish third.
Spurs have the option to extend Alderweireld's deal by an extra 12 months but the Belgian centre-half will be available to sign for £25m.
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Manchester United are reportedly set to complete their fourth signing of the summer, with Belgian worldwide Toby Alderweireld closing in on a move.
It is believed Spurs will look to the likes of Lewis Cook at Bournemouth to replace Dembele, with Pochettino's penchant for developing young talent ideal for these kind of situations as he looks to move on veteran stars.
Manchester United may be forced to turn to either Jerome Boateng or Toby Alderweireld in their pursuit of a new defender this summer after talks with Barcelona's Yerry Mina came to a halt. He has been at Spurs for three seasons and made 21 appearances last season.
A number of clubs around the world have been attempting to land Mina, with Everton and Manchester United seemingly at the front of the queue - but both teams may just be backing off.
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The Old Trafford unit believe that they will get their target inside the next 48 hours.
United now have Eric Bailly, Victor Lindelof, Chris Smalling, Phil Jones and Marcos Rojo at their disposal.
Boateng did not enjoy a good World Cup and age is against him.
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I want that belt, too!" "He's a big dude and I would feel each time we would clash and he would get big shots off". Dillashaw has finally slammed the door shut on his long standing rivalry with former teammate Cody Garbandt.