"I really hope we can look at it and address this, because at the end, you don't even feel that great out there".
When Isner finally slapped a tired forehand wide at 7.46pm local time, there were no wild roars, no fist pumping and no raised arms in celebration from Anderson.
"I can't believe they're going this hard for this long".
While Anderson-Isner was mostly a serving duel with a few longer rallies thrown in, Djokovic and Nadal repeatedly slugged it out from the baseline, chasing each other around the court and coming up with spectacular winners from every corner. He plays Rafael Nadal or Novak Djokovic in Sunday's title clash.
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With Djokovic leading 6-4 3-6 7-6 (11-9) it became the first match since the Centre Court roof was added in 2009 to be stopped due to the strict curfew imposed by Merton Council to avoid disruption to local residents.
Djokovic signs autographs after his semi-final was suspended.
John Isner plays the ball in his semifinal match at Wimbledon on July 13, 2018 in London.
John Isner of the USA leaves the court after being defeated by Kevin Anderson of South Africa in the men's semifinal match at Wimbledon on Friday.
There, they face the victor of the match between Alicja Rosolska and Abigail Spears and the third-seeded Czech pair of Barbora Krejcikova and Katerina Siniakova.
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Anderson and Isner go way back, to their days when they played in college, Isner at Georgia, Anderson at IL. Though Raonic outgunned Isner in that respect - 31 to 25 - he was unable to see through service games as convincingly. However, the American broke right back before forcing a tiebreak. Isner took that set on his third chance, when Anderson flubbed a forehand.
The exhausted players embraced at the net after a classic encounter eventually finished 7-6 (8/6) 6-7 (5/7) 6-7 (9/11) 6-4 26-24 in South African Anderson's favour after six hours and 36 minutes.
Where is Kevin Anderson vs John Isner taking place? .
This is the latest instalment of the most contested rivalry in the men's game, and what a battle it is expected to be.
Second seed Nadal saved a break point at the start of the second set and celebrated holding serve with a trademark upper-cut fist pump.
Marathon man Anderson clinches Wimbledon final spot
Nadal, 32, is back in the semi-finals at Wimbledon for the first time since 2011 when he finished runner-up to Djokovic. The two went back and forth all the way to 12-all, essentially playing a full sixth and seventh set.