"The incident involved multiple inmate on inmate altercations in three housing units", the department said.
A sequence of fights that raged for more than seven hours at a SC prison left seven inmates dead and 17 more needing "outside medical attention", the S.C. Department of Corrections said early Monday.
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Lee County Fire/Rescue said ambulances from at least seven jurisdictions lined up outside the prison to tend to the wounded.
Earlier, state police were called to attend an "ongoing situation" at the the prison.
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The department said the riot erupted yesterday evening at the Lee Correctional Institution in Bishopville, South Carolina and was brought under control at 2.55am local time today. The local coroner's office also responded.
Lee is a maximum-security prison that houses 1,600 inmates, including some of the state's most violent offenders, reports the State. One inmate killed another in February.
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An hours-long prison brawl in SC has left seven inmates dead, reports WRDW.