Channelview Independent School District, which is located east of Houston, has confirmed band students from Channelview High School were on the bus to Houston after a spring break trip.
A passenger bus crashed Tuesday morning on eastbound Interstate 10 at mile marker 57 near the Alabama/Florida line.
Several people were injured and taken to area hospitals, some by air ambulance.
Baldwin County (Ala.) Sheriff Hoss Mack said one person is in critical condition and five are in serious condition after the bus carrying high school students from Houston fell off Interstate 10.
Mack said the bus went about 50 feet down into the ravine.
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A charter tour bus that was transporting Texas band students home from a trip to Disney World lies where it crashed off I-10 in Alabama.
Authorities in Alabama say a charter tour bus carrying students on a school trip from Houston, Texas, has plunged into a ravine, with multiple injuries reported.
Rescuers used every piece of equipment on every truck to reach them, Mack said: "This is what we call an all-out". Chief Deputy Anthony Lowery with the Baldwin County Sheriff's Office.
An official with the bus charter company, First Class Tours of Houston, said the company was working on a statement.
"Everybody is being transferred to a hospital to at least be checked out", he added.
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Mike Burke from Sacred Heart Hospital in Pensacola, Florida, said that hospital received approximately 20 patients from the accident.
A call center was established at 251-972-6807 for family members looking for their relatives who were aboard the bus, authorities said.
The National Transportation Safety Board said it will send six investigators to investigate the crash.
Officials said the Baldwin County Emergency Management Agency facility in Robertsdale, Alabama, would be used as a staging area to reunite non-injured passengers with families.
Mack said it was expected I-10 would remain shut down at least until noon.
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